Saturday, 30 April 2016

DaVita Clinic fined.

This is not the sort of news we'd like to be reporting.
A DaVita dialysis center in Connecticut has been fined by the state for multiple violations. They problems involve hygiene mainly - disinfection routines, hand hygiene practices, water testing procedures and even such unlikely events at a clinic as having a leaky roof, rusty metal equipment and supplements that had passed their expiry dated. In a clinic with rooms at 15C / 60F.
Inspectors found that documentation of assessments were not always fully up to date.
You can read the news item here.

Thursday, 28 April 2016

HPV vaccine may be effective in adolescents with kidney disease, but less so in those with a kidney transplant

Contradictory results have been published about a HPV vaccine, which does well for some patients but is less effective in others.

So what if someone said a vaccine would boost your immune system and help a great deal if you suffered from HVP and cervical cancer was a possibility? Great let me have it is the likeliest response. Unfortunately it's not as helpful if you have already had a transplant.

A recent scientific report says: -
Human papillomavirus (HPV) vaccination stimulates robust and sustained immune responses in girls and young women with chronic kidney disease (CKD) and those on dialysis, but less optimal responses to the vaccine were observed among those with a kidney transplant. The findings, which appear in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN), suggest that HPV vaccination provides considerable benefits for kidney disease and dialysis patients but may not be as beneficial for kidney transplant recipients.
Cervical cancer is the second most common cancer in women worldwide and is almost entirely caused by HPV infections. Girls and young women with CKD, as well as those who have developed kidney failure that requires dialysis or a kidney transplant, have compromised immune systems, and as a result they have a significantly elevated risk of developing cervical cancer and genital warts if they become infected with HPV. Therefore, the potential health benefits of HPV vaccination may be substantial in this vulnerable population.

The scientists found that study participants with CKD and those on dialysis had antibody levels above the threshold that indicates protection from infection, but a significant proportion of patients with kidney transplants showed evidence of an inadequate antibody response.

Further work is planned to help the unfortunate patients who have had a transplant and are at risk of HVP

More details are available here